EVERYTHING ABOUT FENTANYL RESTRICTIONS

phenytoin will decrease the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Closely. Coadministration of fentanyl with CYP3A4 inducers may lead to a lessen in fentanyl plasma concentrations, deficiency of efficacy or, potentially, advancement of the withdrawal syndrome in a affecte

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